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犬と猫の腎臓病リスク検査 L-FABP

L-FABPとは？ 腎臓の近位尿細管の細胞質に局在する「脂肪酸結合タンパク質」です。 尿細管周囲の虚血(血流不全)や尿細管への酸化ストレスにより、尿中に排泄されます1,2。 尿中L-FABPは生きた近位尿細管細胞から生理的に尿中に排泄されるメカニ

Comparative Prognostic Value of Four Urinary Biomarkers for Cardiovascular and Renal Outcomes After Transcatheter Aortic Valve Implantation.

Cardiorenal Med. 2026 doi: doi: 10.1159/000550414.

Amniotic Fluid Neutrophil Gelatinase-Associated Lipocalin and L-Type Fatty Acid-Binding Protein Levels in Predicting Long-Term Prognosis in Fetal Growth Restriction and Preterm Birth: A Preliminary Study.

Front Pediatr. 2026 doi: doi: 10.3389/fped.2025.1712312.

The utility of urinary liver-binding fatty acid protein levels as a promising biomarker for early detection of acute kidney injury following coronary angiography: a pre-post study at Suez Canal University Hospital.

BMC Nephrol. 2025 doi: doi: 10.1186/s12882-025-04681-4.

Renoprotective effects of human L-type fatty acid-binding protein (hL-FABP) in rhabdomyolysis-induced acute kidney injury.

Sci Rep. 2025 doi: doi: 10.1038/s41598-025-34045-9.

慢性腎臓病と高齢者の要介護リスクが関連　運動習慣によるリスク低減の可能性も示唆

■━━━━━━━━━━━━━━━━━━━━━━━━■腎疾患診断用バイオマーカー L-FABP情報サイト■□■□メールマガジン□■□■No.76／2026年1月配信号［医療者向け］https://fabp.jp/?utm_source=mailmagazine&utm_campaign=260

Clinical Utility of Liver-type Fatty Acid-binding Protein (L-fabp), and Tissue Inhibitor of Metalloproteinase-2 and Insulin-like Growth Factor-binding Protein-7 (Timp-2*igfbp-7) as Early Detector for Acute Kidney Injury in Surgical Patients After Cardiopulmonary Bypass.

IJMRA. 2025 doi: https://doi.org/10.36948/ijfmr.2025.v07i06.60086https://doi.org/10.36948/ijfmr.2025.v07i06.60086

Different renoprotective effects of luseogliflozin depend on the renal function at the baseline in patients with type 2 diabetes: A retrospective study during 12 months before and after initiation.

PLoS One. 2021 doi: 10.1371/journal.pone.0248577.PubMed

Renoprotective effects of canagliflozin, a sodium glucose cotransporter 2 inhibitor, in type 2 diabetes patients with chronic kidney disease: A randomized open-label prospective trial.

Diab Vasc Dis Res. 2018 doi: 10.1177/1479164118782872. Epub 2018 Jun 20.PubMed

Urine Liver-Type Fatty Acid Binding Protein; Biomarker for Diagnosing Acute Kidney Injury and Predicting Mortality in Cirrhotic Patients.

SMJ. 2024 doi: https://doi.org/10.33192/smj.v76i4.268004https://he02.tci-thaijo.org/index.php/sirirajmedj/article/view/268004